Regular Show
Regular Show
Ended
The daily surreal adventures of a blue jay and raccoon duo that attempt to deal with their mundane jobs as groundskeepers at the local park.
Theme
Best friend
Psych
Psych
Ended
When a novice sleuth convinces the police he has psychic powers, he and his reluctant best friend are hired on as consultants to help solve complicated cases.
Broad City
Broad City
Ended
Broad City follows two women throughout their daily lives in New York City, making the smallest and mundane events hysterical and disturbing to watch all at the same time.
How I Met Your Mother
How I Met Your Mother
Ended(2005–2014)
A father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
The Big Bang Theory
The Big Bang Theory
Ended
A woman who moves into an apartment across the hall from two brilliant but socially awkward physicists shows them how little they know about life outside of the laboratory.
Boy Meets World
Boy Meets World
Ended
An adolescent with two siblings tests his various theories about life as he endures the trials of growing up alongside a good friend.
Teen Wolf
Teen Wolf
Ended(2011–2017)
An average high school student and his best friend get caught up in some trouble causing him to receive a werewolf bite. As a result they find themselves in the middle of all sorts of dramas in Beacon Hills.
Smallville
Smallville
Ended(2001–2011)
A young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
Threesome
Threesome
Ended(I) (2011–2012)
Threesome is a comedy about three inseparable friends on the verge of 30. Alice lives with her boyfriend Mitch and their gay best friend Richie. Together they form three points of an unlikely triangle, living, laughing, and largin...
Will and Grace
Will and Grace
Ended(1998– )
Gay lawyer Will and straight interior designer Grace share a New York City apartment. Their best friends are gleeful and proud gay Jack and charismatic, filthy-rich, amoral socialite Karen.
Faking It
Faking It
Ended(2014–2016)
After numerous attempts of trying to be popular two best friends decide to come out as lesbians, which launches them to instant celebrity status. Seduced by their newfound fame, Karma and Amy decide to keep up their romantic ruse.
Hullraisers
Hullraisers
Ended
British sitcom adapted from the Israeli sitcom "Little Mom." It follows the ups and downs of life, friendship, and family for three women living in Hull: self-described actress Toni and her sister Paula and best friend Rana.
Mistresses
Mistresses
Ended
Follows the scandalous lives of a group of four girlfriends, each on her own path to self-discovery as they brave the turbulent journey together.
Everyone Is Doing Great
Everyone Is Doing Great
Ended
Seth and Jeremy enjoyed relative success from 'Eternal', a hit television vampire drama. Five years after their show has ended, they lean on each other as they struggle to reclaim their previous level of success and relevance, awk...
The Epic Tales of Captain Underpants
The Epic Tales of Captain Underpants
Ended
Best friends George and Harold scheme together a number of pranks at school involving their principal, whose alter ego is a superhero they created called Captain Underpants.
iCarly 2021
iCarly 2021
Ended
A group of best friends creating a webcast while grappling with everyday problems and adventures.
State of Georgia
State of Georgia
Ended(2011)
Georgia Chamberlain is a confident aspiring actress with a larger-than-life personality who moves to the city from the South in order to make it on Broadway. Along with her quirky best friend and science-geek Jo, she'll pursue her...
Son of a Donkey
Son of a Donkey
Ongoing
Theo leaves home seeking independence but faces adulting challenges: fines, daddy issues, scams. With best friend Johnny, he learns through mishaps that family matters most.
Hitmen
Hitmen
Ended
Fran and Jamie are best friends and business partners - they just happen to kill people for a living. Having stumbled into a career in contract killing, the misfit duo are definitely not your typical killers for hire.
How I Met Your Father
How I Met Your Father
Ended
Sophie and her close-knit group of friends are in the midst of figuring out who they are, what they want out of life, and how to fall in love in the age of dating apps and limitless options.